Regulation of Stem Cell Metabolism by the Lin28/let-7 Axis
My PhD thesis is focused on two fundamental aspects of stem cell metabolism: (1) the role of Lin28 in programming stem cell metabolism, and (2) how metabolism in turn fuels and governs pluripotency. Our studies led us to discover that the stem cell factor Lin28a promotes gigantism by enhancing gluco...
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| Language: | en_US |
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Harvard University
2014
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| Online Access: | http://dissertations.umi.com/gsas.harvard:11217 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11745726 |