Serum and Glucocorticoid-Regulated Kinase Signaling in Breast Cancer

Serum and Glucocorticoid-Regulated Kinase Signaling in Breast Cancer

Oncogenic activating mutations in PIK3CA, the gene encoding the catalytic subunit of phosphoinositide 3-kinase (PI 3-K), are highly prevalent in breast cancer. The protein kinase Akt is considered to be the primary effector of PIK3CA, though the mechanisms by which PI 3-K mediates tumorigenic signal...

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Bibliographic Details
Main Author: Gasser, Jessica Ann
Other Authors: Toker, Alex
Language:en_US
Published: Harvard University 2014
Subjects:
Cellular biology
Molecular biology
Biology
breast cancer
INPP4B
PIK3CA
SGK3
signal transduction
Online Access:http://dissertations.umi.com/gsas.harvard:11296
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11745712

Internet

http://dissertations.umi.com/gsas.harvard:11296
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11745712

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