Toward Multiplex Genome Engineering in Mammalian Cells
Given the explosion in human genetic data, new high-throughput genetic methods are necessary for studying variants and elucidating their role in human disease. In Chapter I, I will expand on this concept and describe current methods for genetically modifying human cells. In E. coli, Multiplex Autom...
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| Language: | en_US |
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Harvard University
2013
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| Online Access: | http://dissertations.umi.com/gsas.harvard:11179 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11181203 |