Hidden Markov Models Predict Epigenetic Chromatin Domains

Hidden Markov Models Predict Epigenetic Chromatin Domains

Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. We developed computational methods to analyze the combinatorial effect and large-scale organizations of genome-wide distributions of epigenetic marks. Throughout this dissertation, we sho...

Full description

Bibliographic Details
Main Author: Larson, Jessica
Other Authors: Yuan, Guo-Cheng
Language:en_US
Published: Harvard University 2012
Subjects:
biostatistics
bioinformatics
chromatin
chromatin domains
epigenetics
hidden Markov models
histone modifications
Online Access:http://dissertations.umi.com/gsas.harvard:10105
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10087396

Internet

http://dissertations.umi.com/gsas.harvard:10105
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10087396

Similar Items