Molecular Mechanisms That Contribute to Spindle Assembly Checkpoint Inactivation
The Spindle Assembly Checkpoint (SAC) prevents anaphase onset in response to chromosome attachment defects. Bipolar kinetochore attachment is required for SAC silencing which allows for anaphase onset and the release of the phosphatase, Cdc14. The Cdc14 early anaphase release (FEAR) pathway reverses...
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Format: | Others |
Language: | English English |
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Florida State University
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Online Access: | http://purl.flvc.org/fsu/fd/2018_Su_Bokros_fsu_0071E_14734 |