Characterization of the Iron Dependent Regulator and Its Hyperactive Mutant from Mycobacterium Tuberculosis

The Iron-dependent Regulator (IdeR) is a 230-amino acid transcriptional repressor that regulates iron homeostasis, oxidative stress response and virulence in Mycobacterium tuberculosis. IdeR binds to DNA as a dimer of dimers to repress gene expression and as four dimers to upregulate gene expression...

Full description

Bibliographic Details
Other Authors: Walker, Lawrence (authoraut)
Format: Others
Language:English
English
Published: Florida State University
Subjects:
Online Access:http://purl.flvc.org/fsu/fd/FSU_migr_etd-8061