Generation and Characterization of Fret Constructs of Cardiac Troponin C to Study Divalent Cation-Dependent Structural Changes and Develop a Ca2+ Sensor
Troponin C (TnC), the Ca2+ binding subunit in striated muscle, is central to regulation of contraction. Binding of Ca2+ to TnC results in a series of conformational changes in the different regulatory proteins, which ultimately leads to muscle contraction. From structural studies about Troponin C, w...
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| Format: | Others |
| Language: | English English |
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Florida State University
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| Online Access: | http://purl.flvc.org/fsu/fd/FSU_migr_etd-7700 |