The Effect of Copper Deficiency and Toxicity on the Tumor Suppressor Protein P53
Transcription of the p53 gene is stimulated by DNA damage. Newly synthesized p53 is translocated to the nucleus where it binds DNA and acts as a transcription factor to regulate gene transcription, suppress the cell cycle, and halt cellular proliferation. It has been hypothesized that cell cycle arr...
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| Format: | Others |
| Language: | English English |
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Florida State University
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| Online Access: | http://purl.flvc.org/fsu/fd/FSU_migr_etd-1680 |