Identification and Phenotypic Plasticity of Metastatic Cells in a Mouse Model of Melanoma
Melanoma is the deadliest form of skin cancer due to its high propensity to metastasize and resistance to current therapies. We have created a spontaneous mouse model of metastatic melanoma (Dct-Grm1/K5-Edn3) where metastasis to the lungs is 80% penetrant. The primary tumors of these mice present ce...
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| Format: | Others |
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FIU Digital Commons
2017
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| Online Access: | http://digitalcommons.fiu.edu/etd/3472 http://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=4286&context=etd |