Development of a MALDI-TOF-MS Method for the Analysis of Cyanobacterial Neurotoxin β-N-Methylamino-L-alanine (BMAA) in Search of BMAA Incorporation in Biological Samples

Development of a MALDI-TOF-MS Method for the Analysis of Cyanobacterial Neurotoxin β-N-Methylamino-L-alanine (BMAA) in Search of BMAA Incorporation in Biological Samples

Beta-N-methylamino-L-alanine (BMAA) is a non-protein amino acid produced by many cyanobacteria, and thought to induce neurotoxic effects through excitotoxicity, contributing to neurodegenerative diseases such as Amyotrophic Lateral Sclerosis/Parkinsonism-dementia complex (ALS-PDC) and Alzheimer’s. T...

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Bibliographic Details
Main Author: Conklin, Laura M
Format: Others
Published: FIU Digital Commons 2015
Subjects:
MALDI-TOF-MS
cyanobacteria
BMAA
MALDI
β-N-Methylamino-L-alanine
neurotoxin
Parkinson's
PDC
neurodegenerative diseases
ALS
quantitation
Analytical Chemistry
Biochemistry
Environmental Chemistry
Online Access:http://digitalcommons.fiu.edu/etd/2275
http://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=3463&context=etd

Internet

http://digitalcommons.fiu.edu/etd/2275
http://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=3463&context=etd

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