Physiological and non-physiological regulation of indoleamine-2,3-dioxygenase
The heme enzyme indoleamine 2,3-dioxygenase (IDO) catalyses L-tryptophan (LTrp) oxidation along the kynurenine pathway and is a key regulator of the mammalian immune system. It’s unknown if the enzyme is under redox control and the use of new potent inhibitors of IDO represents a novel therapeutic a...
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Format: | Others |
Language: | English |
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Florida Atlantic University
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Online Access: | http://purl.flvc.org/fau/fd/FA00004256 |