Murine glucose-6-phosphatase-beta deficiency is associated with neutropenia, neutrophil dysfunction, reduced fertility and pregnancy-associated mortality.
G6Pase-alpha and G6Pase-beta share kinetic properties and active site structures, which lie on the luminal side of the endoplasmic reticulum (ER). For hydrolysis of G6P to glucose, G6Pase-alpha or G6Pase-beta must couple with an ubiquitously expressed ER-transmembrane protein, the G6P transporter (G...
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Format: | Others |
Language: | English Chinese |
Published: |
2009
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Online Access: | http://library.cuhk.edu.hk/record=b6075315 http://repository.lib.cuhk.edu.hk/en/item/cuhk-344948 |