Suppression of thromboxane synthase inhibits lung cancer cell proliferation.
Further studies were done to investigate the mechanism responsible for 1-BI-induced apoptosis in NCI-H460. It was found that 1-BI stimulated the expression of pro-apoptotic p53, Bax and cytosolic NF-kB p65 subunit but decreased pERK in NCI-H460 cells. The active forms of caspase 3 and caspase 9 were...
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| Format: | Others |
| Language: | English Chinese |
| Published: |
2008
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| Online Access: | http://library.cuhk.edu.hk/record=b6074592 http://repository.lib.cuhk.edu.hk/en/item/cuhk-344225 |