Role of nitric oxide (NO), NO synthases and soluble guanylyl cyclase/cGMP/protein kinase G signaling pathway in the regulation of apoptosis and cell proliferation in pancreatic islets and ovarian cancer cells.
In the studies about ovarian cancer cells, basal iNOS expression in the chemosensitive OV2008 cells was significantly higher than in the chemoresistant C13* cells. Cisplatin further increased iNOS expression in OV2008 cells, but had no effect in C13* cells. Furthermore, cisplatin dramatically reduce...
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| Format: | Others |
| Language: | English Chinese |
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2006
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| Online Access: | http://library.cuhk.edu.hk/record=b6074229 http://repository.lib.cuhk.edu.hk/en/item/cuhk-343858 |