The pH-sensing mechanism of antibody recycling by the neonatal Fc receptor revealed using free energy perturbation calculations
The immune system produces antibodies to recognize and provide protection against infection. The immunoglobulin G (IgG) antibody isotype is present at high serum concentrations and has a longer half-life than other isotypes due to the interaction between its fragment crystallizable (Fc) region with...
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Language: | English |
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2021
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Online Access: | https://doi.org/10.7916/d8-kt1q-rp07 |