Microproteins and Epigenetic Remodeling in Cancer and Aging

The plant homeodomain 6 gene (PHF6) is frequently mutated in human T-cell acute lymphoblastic leukemia (T-ALL); however, its specific functional role in leukemia development remains to be established. Here, we show that loss of PHF6 is an early mutational event in leukemia transformation. Mechanisti...

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Bibliographic Details
Main Author: Quinn, Stuart Aidan
Language:English
Published: 2021
Subjects:
Online Access:https://doi.org/10.7916/d8-hwat-bq40