Microproteins and Epigenetic Remodeling in Cancer and Aging
The plant homeodomain 6 gene (PHF6) is frequently mutated in human T-cell acute lymphoblastic leukemia (T-ALL); however, its specific functional role in leukemia development remains to be established. Here, we show that loss of PHF6 is an early mutational event in leukemia transformation. Mechanisti...
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Language: | English |
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2021
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Online Access: | https://doi.org/10.7916/d8-hwat-bq40 |