Elucidating Regulatory Mechanisms of Cardiac CaV1.2 and NaV1.5 Channels
In the heart, sodium (Na+) influx via NaV1.5 channels initiates the action potential, and calcium (Ca2+) influx via CaV1.2 channels has a key role in excitation-contraction coupling and determining the plateau phase of the action potential. Mutations in the genes that encode these ion channels or in...
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Language: | English |
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2021
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Online Access: | https://doi.org/10.7916/d8-8k7q-6148 |