Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex

Most eukaryotic pre-mRNAs undergo 3′-end cleavage and polyadenylation prior to their export from the nucleus. A large number of proteins in several complexes participate in this 3′-end processing, including cleavage and polyadenylation specificity factor (CPSF) in mammals. The CPSF can be further...

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Bibliographic Details
Main Author: Hamilton, Keith
Language:English
Published: 2021
Subjects:
Online Access:https://doi.org/10.7916/d8-6xaw-xv26