Quantitative and dynamic analysis of the focused-ultrasound induced blood-brain barrier opening in vivo for drug delivery
The rate limiting factor for the treatment of neurodegenerative diseases is the blood-brain barrier (BBB), which protects the brain microenvironment from the efflux of large molecules, and thus it constitutes a major obstacle in therapeutic drug delivery. All state-of-the-art strategies to circumven...
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Language: | English |
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2015
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Online Access: | https://doi.org/10.7916/D8SN07VT |