Dissecting Dopamine D2 Receptor Signaling

Dopamine D2 receptor (D2R) is a G protein-coupled receptor (GPCR) that activates G protein and arrestin signaling molecules. D2R antagonism has been a hallmark of antipsychotic medications for more than half a century. However, this drug-class is associated with substantial side effects that decreas...

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Bibliographic Details
Main Author: Donthamsetti, Prashant Chandra
Language:English
Published: 2015
Subjects:
Online Access:https://doi.org/10.7916/D8QN660V