Methodological Innovations in Polyketide Synthesis and their Application toward the Scalable Synthesis of Anti-Tumor Agent Spongistatin 1

This thesis describes the efforts of the Leighton laboratory to develop a scalable synthetic route to access anti-tumor agent spongistatin 1, or analogs thereof. In an effort to achieve this goal, several new chemical reaction platforms were established. Though these novel chemical transformations w...

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Bibliographic Details
Main Author: Reznik, Samuel Kaye
Language:English
Published: 2012
Subjects:
Online Access:https://doi.org/10.7916/D8Q246C5