Designer Exons Inform a Biophysical Model for Exon Definition
Pre-mRNA molecules in humans contain mostly short internal exons flanked by long introns. To explain the removal of such introns, recognition of the exons instead of recognition of the introns has been proposed. This thesis studies this exon definition mechanism using a bottom-up approach. To reduce...
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| Language: | English |
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2013
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| Online Access: | https://doi.org/10.7916/D8P55T7X |