HDAC6 activity is required for efficient polarization and intracellular transport of organelles in directionally migrating cells

Deacetylation of non-histone substrates by histone deacetylase 6 (HDAC6) has been shown to affect chemotactic invasion (e.g., Haggarty et al., 2003; Hubbert et al., 2002; Tran et al., 2007) or wound healing motility (Lafarga et al., 2012) of fibroblasts. Chemotactic invasion and wound-healing motili...

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Bibliographic Details
Main Author: Salam, Ambar Asghar
Language:English
Published: 2013
Subjects:
Online Access:https://doi.org/10.7916/D8KD257D