Using the natural resistance of motor neuron subpopulations to identify therapeutic targets in amyotrophic lateral sclerosis
Though mutant proteins are broadly expressed in neurodegenerative diseases, only some neuronal subsets are vulnerable. In patients with amyotrophic lateral sclerosis (ALS), most motor neurons degenerate but those innervating extraocular muscles, pelvic sphincters and slow limb muscles exhibit select...
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| Language: | English |
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2014
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| Online Access: | https://doi.org/10.7916/D8FN145W |