A Multi-Scale Approach Investigating the Physiological Relevance of APC-Dia-Microtubule Mediated Actin Assembly in the Drosophila Ovary
The multifunctional Adenomatous polyposis coli (APC) proteins negatively regulate Wnt signaling, stabilize microtubules, and indirectly regulate actin through effectors such as Asef and IQGAP. We have shown that both vertebrate APC (vAPC) and Drosophila APC1 through their basic domains can bundle an...
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| Format: | Others |
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Research Showcase @ CMU
2015
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| Online Access: | http://repository.cmu.edu/dissertations/617 http://repository.cmu.edu/cgi/viewcontent.cgi?article=1655&context=dissertations |