Probing the active site of anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis to facilitate novel drug development
Caused by the organism Mycobacterium tuberculosis (Mtu), the globally distributed disease tuberculosis was responsible for the deaths of 1.4 million people in 2011. Anthranilate phosphoribosyltransferase (AnPRT) is an enzyme that catalyses the second committed step of the tryptophan biosynthetic pat...
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| Language: | en |
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University of Canterbury. Chemistry
2014
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| Online Access: | http://hdl.handle.net/10092/9049 |