Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized app mouse model
Alzheimer’s disease is characterized by the formation of two major pathological hallmarks: amyloid plaques and neurofibrillary tangles. Although there have been many studies to understand the role of microglia in Alzheimer’s disease, it is not yet known how microglia can promote disease progression...
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| Language: | en_US |
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2021
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| Online Access: | https://hdl.handle.net/2144/42695 |