The role of proteotoxicity and cross-organelle stress response in drug-induced acute kidney injury

Nephrotoxicity is a dose-limiting side effect of gentamicin that accounts for a significant portion of clinical acute kidney injury (AKI). The mechanism of gentamicin-induced nephrotoxicity is uncertain and effective therapy for gentamicin-induced renal cell injury is limited by incomplete mechanis...

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Bibliographic Details
Main Author: Igwebuike, Chinaemere
Other Authors: Borkan, Steven C.
Language:en_US
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/2144/41106