Nanoparticles modulate lysosomal acidity and autophagic flux to rescue cellular dysfunction
Autophagy is a critical cellular maintenance machinery in cells, and prevents the accumulation of toxic protein aggregates, organelles or lipid droplets through degradation via the lysosome. In macro-autophagy, autophagosome first engulfs around aggregates or cellular debris and subsequently fuses w...
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Language: | en_US |
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2020
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Online Access: | https://hdl.handle.net/2144/41021 |