Metabolic regulation of insulin secretion: the link between excess glucose, mechanistic target of rapamycin complex 1 & hyperinsulinemia

Obesity, a major risk factor in the development of Type 2 Diabetes (T2D), is commonly associated with insulin resistance and hyperinsulinemia. The long accepted view has been that insulin resistance drives hyperinsulinemia; however, there are multiple lines of evidence that hyperinsulinemia can p...

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Bibliographic Details
Main Author: Rumala, Courtney
Other Authors: Rameh, Lucia E.
Language:en_US
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/2144/38590