Crosstalk between lipid metabolism and mitochondrial bioenergetics in tuberous sclerosis complex
BACKGROUND: Tuberous sclerosis complex (TSC) is a multisystem hamartomatous disease caused by inactivating mutations in the TSC1/TSC2 genes leading to hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) in TSC tumors. Novel therapeutic regimens and imaging biomarkers remain critical...
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| Language: | en_US |
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2019
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| Online Access: | https://hdl.handle.net/2144/36538 |