Titanium-alkoxide based reductive coupling and medicinal chemistry for treatment of porphyromonas gingivalis-induced oral diseases
Both enantiomers of highly enantioenriched chiral allenylsilanes were prepared in high yields through a scalable synthetic sequence, employing a modified copper-mediated SN2’ reaction. These reagents were utilized in the asymmetric three-component propargylation reactions to produce enantioenriched...
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| Language: | en_US |
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2019
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| Online Access: | https://hdl.handle.net/2144/33251 |