Using Saccharomyces cerevisiae to study the role of the X family DNA polymerase POL4 in CRISPR/Cas9-induced mutation
The yeast repair DNA polymerase POL4 is part of the X family of DNA polymerases that function in DNA repair, specifically in gap filling for non-homologous end joining (NHEJ). POL4 is the only Pol X family polymerase in Saccharomyces cerevisiae and has been shown to have a role in creating deletions...
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Language: | en_US |
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2019
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Online Access: | https://hdl.handle.net/2144/33216 |