Using Saccharomyces cerevisiae to study the role of the X family DNA polymerase POL4 in CRISPR/Cas9-induced mutation

The yeast repair DNA polymerase POL4 is part of the X family of DNA polymerases that function in DNA repair, specifically in gap filling for non-homologous end joining (NHEJ). POL4 is the only Pol X family polymerase in Saccharomyces cerevisiae and has been shown to have a role in creating deletions...

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Bibliographic Details
Main Author: Zhang, Richard
Other Authors: Celenza, John L.
Language:en_US
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/2144/33216