A reduction in the RNA binding protein TIA1 protects against neurodegeneration, rescues behavioral deficits and prolongs survival

A reduction in the RNA binding protein TIA1 protects against neurodegeneration, rescues behavioral deficits and prolongs survival

RNA binding proteins (RBPs) have been found to be frequently involved in neurodegenerative diseases (Ash 2014). Mutations in RBPs cause amyotrophic lateral sclerosis (ALS), spinocerebellar ataxia, frontotemporal dementia (FTD) and myopathies (Ash 2014), and recent studies suggest that aggregation of...

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Bibliographic Details
Main Author: Randhawa, Anantbir
Other Authors: Gerstenfeld, Louis C.
Language:en_US
Published: 2018
Subjects:
Medicine
Neurodegeneration
Neuroinflammation
Stress granules
Tau
Tauopathies
T-cell intracellular antigen 1
Online Access:https://hdl.handle.net/2144/31265

Internet

https://hdl.handle.net/2144/31265

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