Synergistic effects of combining PARP inhibitor (AZD2281) and ATR inhibitor (AZD6738) in Ewing Sarcoma cell lines

Ewing Sarcoma (ES) is an aggressive pediatric solid tumor. Even though overall-survival for localized patients is approximately 70%, the overall-survival for high risk ES patients has not improved in the last 20 years. Therefore, there is a need for exploration of new therapeutic agents in ES. Recen...

Full description

Bibliographic Details
Main Author: Meyer, Stephanie C.
Other Authors: Franzblau, Carl
Language:en_US
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/2144/30818