Role of mitochondrial dysfunction in the development of nutrient-induced hyperinsulinemia
Pancreatic beta cells sense fluctuations in circulating nutrients and adjust the rate of insulin secretion to maintain glucose homeostasis. Mitochondria integrate changes in nutrient flux to the generation of signals that modulate insulin secretion via oxidative phosphorylation. Type 2 Diabetes (T2D...
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| Language: | en_US |
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2018
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| Online Access: | https://hdl.handle.net/2144/29271 |