Engineering a regulatory framework for synthetic self-amplifying RNA circuits
Self-amplifying RNA replicons are an attractive alternative to traditional nucleic acid therapeutics, providing high, sustained expression from a low dose, without the risk of genomic integration. Replicons are derived from a viral genome, but utilize viral self-amplification to produce heterologous...
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| Language: | en_US |
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2017
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| Online Access: | https://hdl.handle.net/2144/23683 |