Transthyretin gene regulation in wild-type transthyretin amyloidosis
Wild-type transthyretin amyloidosis (ATTRwt) is a rare, sporadic protein misfolding disorder with no validated biomarkers or specific treatments. The disease is characterized by deposition of amyloid fibrils composed of wild-type transthyretin (TTR) in cardiac tissue, which leads to cardiomyopathy,...
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| Language: | en_US |
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2017
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| Online Access: | https://hdl.handle.net/2144/20799 |