Evaluation and extension of a kernel-based method for gene-gene interaction tests of common variants

Interaction is likely to play a significant role in complex diseases, and various methods are available for identifying interactions between variants in genome-wide association studies (GWAS). Kernel-based variance component methods such as SKAT are flexible and computationally efficient methods for ide...

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Bibliographic Details
Main Author: Xue, Luting
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/19565