Novel T-cell receptor mediated mechanisms of Notch activation and signaling
The Notch receptor is an evolutionarily highly conserved transmembrane protein essential to a wide spectrum of cellular systems. Notch is especially important to T-cell development, and its deregulation leads to leukemia. Although not well characterized, Notch signaling continues to play an integral...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/19064 |