Quantitative studies of RET activation, deactivation and trafficking kinetics upon stimulation by its natural ligand Artemin
Receptor tyrosine kinases (RTKs) are key regulators of critical cellular processes, such as cell cycle, differentiation, proliferation, apoptosis and survival. Mutations, hyperactivity and loss of function of RTKs are responsible for numerous diseases. Because of the therapeutic importance of RTK si...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/17712 |