Depletion of L2pB1 cells increases abdominal inflammation, blood lipids, and glucose intolerance in DIO mice

L2pB1 cells are a subset of B-1 B lymphocytes expressing programmed death ligand 2 (PD-L2) on their surface. They constitute 30-50% of B lymphocytes in the mouse peritoneal cavity and contribute to the production of natural IgM antibody. Previous studies have indicated a protective role of B-1 B cel...

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Bibliographic Details
Main Author: Newmark, Jordan Alison
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/16760