The role of matrin 3 in the pathogenesis of amyotrophic lateral sclerosis
The cause of amyotrophic lateral sclerosis (ALS), a cruel neurodegenerative disease, remains unclear. Trans-activating response region (TAR) DNA-binding protein of 43 kDa (TDP-43) has been suggested to have an important role in ALS pathogenesis. In this thesis, we show that a disease linked mutation...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/16177 |