Hydroxyl radical cleavage of nucleic acids: understanding RNA cleavage profiles and identifying DNA structural motifs

High-resolution techniques to characterize the three-dimensional structure of nucleic acids are critical for understanding the mechanisms of action of biologically important RNA and DNA molecules. Methods based on chemical probing have been particularly useful in gaining insight into the structures...

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Bibliographic Details
Main Author: Azad, Robert Navid
Language:en_US
Published: 2016
Subjects:
DNA
RNA
Online Access:https://hdl.handle.net/2144/15123