The development of intratumoral heterogeneity in ovarian tumors: role of cancer stem cells in disease progression

Like with many cancers, a single ovarian tumor can display remarkable diversity in genetics, epigenetics, expression profiles, microenvironment and cell differentiation and plasticity. This so-called intratumoral heterogeneity (ITH) is thought to greatly increase mortality by enabling tumors to adap...

Full description

Bibliographic Details
Main Author: Lunsford, Elaine Patricia
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/14678