The development of intratumoral heterogeneity in ovarian tumors: role of cancer stem cells in disease progression
Like with many cancers, a single ovarian tumor can display remarkable diversity in genetics, epigenetics, expression profiles, microenvironment and cell differentiation and plasticity. This so-called intratumoral heterogeneity (ITH) is thought to greatly increase mortality by enabling tumors to adap...
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Language: | en_US |
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2016
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Online Access: | https://hdl.handle.net/2144/14678 |