Serum amyloid A and toll-like receptor 2 regulate vascular smooth muscle cell cholesterol trafficking and differentiation

Vascular smooth muscle cells (SMCs) regulate vessel contraction but during diseases including atherosclerosis, SMCs undergo functional changes that contribute to pathology. Chronic inflammation in the vasculature exacerbates disease progression. Acute phase serum amyloid A (SAA) is up-regulated dur...

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Bibliographic Details
Main Author: Pessolano, Lawrence
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/14599