Ligand selectivity: binding at the protein-protein interface of Keap1 and NEMO
This dissertation comprises identifying the structural determinants of binding selectivity as demonstrated in three systems. The first system involves the structure determination of Keap1-small molecule fragment complexes to locate binding surfaces. The second system involves the structural...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/14550 |