The importance of specific amino acid residues in transmembrane domains 3 and 5 of a corticotropin releasing-factor receptor for functional activity of a CRF-R1 selective small molecule antagonist
INTRODUCTION: For many years, stress and anxiety disorders have taken a heavy toll on the American population. Affecting approximately 40 million individuals over the age of 18, the discovery of treatment options is very important. Ever since the 1950s, a wide variety of compounds have been discover...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/14391 |