Organocatalytic acid mediated Mannich reactions and multicomponent boronate reactions to make chiral benzhydrils
Since its discovery in 1912, the Mannich reaction has been widely utilized in organic chemistry to form C-C bonds. Reactivity of an enol with an imine allows for easy formation of a [beta]-aminoketone. Enamines have also been widely utilized as convenient nucleophiles. In our work, unexpected reac...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/14248 |