Mechanistic differences in interactions of HIV-1 and HIV-2 with dendritic cells
Pathogenic mechanisms that account for the dramatic differences between the HIV-1 and HIV-2 epidemics remain unknown. Myeloid dendritic cells (DCs) are sentinels of the immune system, which sense invading pathogens and initiate immune responses. I hypothesize that failure of HIV-2 to overcome DC-int...
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Language: | en_US |
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2016
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Online Access: | https://hdl.handle.net/2144/13991 |